Polyploid newts maintain normal kidney tubule diameters using fewer, larger cells.

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

• Newt kidney tubule cells produce correct tubule diameter using fewer cells when cell size is enlarged; a single enlarged cell can loop to achieve the same diameter (Fankhauser 1945).finding0.888
  Shows multi-scale anatomical homeostasis using different cellular mechanisms.
• Newt kidney tubule lumen diameter is maintained with fewer, larger cells by switching to a single-cell wrapping mechanismfinding0.873
  When cell size is artificially enlarged, tubule formation adapts by reducing cell count and eventually using cytoskeletal bending within one cell.
• Enlarged newt cells compensate for increased size by adjusting cell number and can form kidney tubule from a single cell wrapped around itself.finding0.870
  When cell size was doubled, tubules used fewer cells; when quadrupled, a single cell formed the tubule by cytoskeletal deformation, maintaining correct lumen diameter.
• Single newt cell can wrap around itself to form a kidney tubule when cell size is artificially increased.finding0.867
  From Fankhauser (1945), demonstrates diverse molecular mechanisms serving a higher-level anatomical specification.
• Enlarged polyploid cells produce normal-sized kidney tubules by adjusting cell number and using cytoskeletal bendingfinding0.865
  Shows diverse molecular mechanisms serve higher-level anatomical specification despite radical changes in cell size and quantity.
• Newt kidney tubule cells, when artificially enlarged, can bend a single cell around itself to achieve correct tubule diameter, illustrating top-down control over molecular mechanisms.claim0.858
  Extreme example of regulative flexibility.
• Polyploid Newt Kidney Tubule Adaptationfinding0.849
  Engineered polyploid newts with abnormally large cells and extra chromosomes develop normal kidney tubule diameters by switching molecular mechanisms on-the-fly.
• Polyploid Newt Kidney Size Compensationfinding0.837