Planarian flatworms are extremely resistant to transgenesis, aging, cancer, and injury despite incredibly noisy genome.

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• Planarian flatworms contain voltage patterns in non-neural cells that are re-writable latent pattern memories guiding future regenerative anatomy, editable without touching the genome.finding0.858
  Key empirical result demonstrating a sharp distinction between the cellular machine and the data it uses, analogous to false memory inception
• Trained planarian flatworms regenerating new heads retain memory of learned behaviors, with behavioral engrams imprinted on newly formed brain tissue.finding0.820
  Evidence that memory and anatomical form are tightly linked; information processing enables integration of behavioral and morphological change.
• Planarians maintain high regenerative fidelity despite genetic heterogeneity and chromosomal variationfinding0.806
• Planarian bioelectric circuits can enter a metastable cryptic state where they stochastically produce one- or two-headed worms upon each amputation, analogous to perceptual bistability.claim0.795
  Links cognitive and morphogenetic dynamics.
• Planaria represent an extreme case where the ratchet has run fully, producing a functional body almost regardless of genome, making them recalcitrant to genetic manipulation.claim0.791
  Specific application of the ratchet claim.
• Planarian Flatworm (Planaria)concept0.789
  Model organism demonstrating regeneration, behavioral memory imprinting on new brains, and rewritable bioelectric pattern memory; key example of basal cognition.
• Gap junction blockade stochastically induces heads of other planarian species in genetically wild-type worms.finding0.786
  Temporary disruption of gap junctions causes planaria to reconstruct heads appropriate to other species, revealing latent morphospace attractors.
• Modification of cell-cell communication during planarian regeneration causes genetically-normal fragments to produce heads appropriate to other species (Emmons-Bell et al. 2015, Sullivan et al. 2016)finding0.775
  Shows that morphological attractors can be switched via physiological cues, revealing the navigation of morphospace by collectives.