Fragments of 2-headed planarians continue regenerating as 2-headed indefinitely despite normal genome

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

• Planarian fragments regenerate with near 100% fidelity of anatomical structurefinding0.858
  Planarians cut into pieces regenerate precisely what is missing and re-scale tissue to form complete worms.
• Modification of cell-cell communication during planarian regeneration causes genetically-normal fragments to produce heads appropriate to other species (Emmons-Bell et al. 2015, Sullivan et al. 2016)finding0.835
  Shows that morphological attractors can be switched via physiological cues, revealing the navigation of morphospace by collectives.
• The same wild-type genome can produce 1-, 2-, or 0-headed planaria depending on bioelectric history, showing that anatomical outcome is not directly encoded in the genome.claim0.830
  Demonstrates the role of epigenetic bioelectric software.
• Planarian fragments regenerating from bioelectrically re-patterned tissue produce permanent two-headed phenotype, demonstrating transient bioelectric states can produce lasting morphological memory changes.finding0.830
  Key evidence that morphogenetic memories are stored in bioelectric circuits and are rewritable via transient voltage state modifications; memory persists across multiple regeneration cycles.
• Planarians derived from tail fragments of trained worms retain original information after brain regenerationfinding0.829
  Behavioral memories in planaria persist through complete brain regeneration, indicating movement of memory across tissues.
• Planarians maintain high regenerative fidelity despite genetic heterogeneity and chromosomal variationfinding0.816
• Transient perturbation of bioelectric states produces stable two-headed planaria that regenerate truefinding0.807
  Manipulating gap junctions or ion channels can permanently alter the target morphology in planaria, resulting in two-headed animals that regenerate two heads without further intervention.
• Planarian Two-Headed Regeneration via Bioelectric Circuit Rewritingfinding0.806