Pattern memory in planaria can be re-written non-genetically via transient modification of membrane potential, leading to permanent changes in target morphology.

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• Transient bioelectrical modulation of body-wide pattern memory circuits in planaria can shift them from one-headed to persistent two-headed state, persisting through amputation rounds until reset with different manipulation.finding0.852
  Experimental evidence that organism-scale goals can be rewritten through physiological signals without genetic modification; demonstrates bioelectricity as cognitive medium.
• Planarian pattern memory is encoded in bioelectric attractor states within gap-junction-coupled networks, which can be re-written by channel modulation.hypothesis0.849
  Testable by computational modeling and experimental perturbation of specific bioelectric circuits.
• Planarian flatworms contain voltage patterns in non-neural cells that are re-writable latent pattern memories guiding future regenerative anatomy, editable without touching the genome.finding0.838
  Key empirical result demonstrating a sharp distinction between the cellular machine and the data it uses, analogous to false memory inception
• Planaria maintain memories and re-imprint them from tail fragments onto newly regenerating brains.finding0.826
  Example of memory dynamics during extreme regeneration.
• Planaria have fully committed to a strategy that overrides genetic details with large-scale pattern completion.claim0.819
  Interpretive claim explaining planarian robustness as top-down morphogenetic intelligence.
• Manipulation of resting potential pattern in planaria stably alters target morphology (head number) despite wild-type genetics.finding0.812
  Transient bioelectric perturbation with ion channel drugs/RNAi permanently alters the number of heads regenerated even in subsequent rounds without further treatment, demonstrating bioelectric pattern memory.
• Planarian fragments regenerating from bioelectrically re-patterned tissue produce permanent two-headed phenotype, demonstrating transient bioelectric states can produce lasting morphological memory changes.finding0.810
  Key evidence that morphogenetic memories are stored in bioelectric circuits and are rewritable via transient voltage state modifications; memory persists across multiple regeneration cycles.
• Planaria permanently generate two-headed forms despite completely wild-type genetic sequence after bioelectric pattern rewriting.finding0.810
  Demonstrates that anatomical outcomes can be reprogrammed at the bioelectric level independently of DNA, inverting the software/hardware metaphor