finding
active
finding:mammalian-embryos-overcome-drastic-perturbations-such-as-amputation-and-early-embryo-splitting-results-in-normal-monozygotic-twinsMammalian embryos overcome drastic perturbations such as amputation, and early embryo splitting results in normal monozygotic twins.
Demonstrates mammalian regulative capacity and robust self-organization.
Source paper
extracted_from(2023) · Watson, Richard · Levin, Michael
Neighborhood — ranked by edge-count
Claims (1)
claim
- Rejects reductionist genetic determinism in morphogenesis.
Related by similarity (8)
cosine ≥ 0.65 · no typed edgeEntities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.
- Classic regulative-development evidence for goal-directed (not merely mechanical) morphogenesis.
- Temporary introduction of breaks in the embryonic blastoderm results in twins, triplets, etc. (Lutz 1949)finding0.798Demonstrates that the blastoderm is a dynamical excitable medium where multiple coherent embryos can self-organize, not fixed by genetics.
- Stress-sharing embryos achieve perfect sequential target patterns; non-sharing limited to <1% improvement.finding0.791Stress-sharing embryos formed each sequential target with stress reducing to zero; non-sharing achieved only tiny improvements.
- Empirical support for the claim that the number of selves in an embryo is not genetically fixed.
- Evidence of morphogenetic problem-solving and anatomical homeostasis across serious perturbations; demonstrates collective intelligence in development.
- Shows stress sharing allows perfect formation of part-by-part target patterns.
- Waves of ATP mediate morphogenetic information sharing and teratogen resistance among groups of embryos.finding0.771Tung et al. 2024 finding on cross-embryo morphogenetic assistance (CEMA).
- Sharing of stress between cells facilitates morphogenesis and increases robustness of morphogenetic outcomes.hypothesis0.761Prior hypothesis tested in the paper; from Levin 2022.