Keratocytes migrate to the cathode, but keratocyte fragments migrate to the anode (Sun et al. 2013)

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• Fragments of keratocytes move opposite to whole cells in an electric field.finding0.840
  From Sun et al. 2013; demonstrates that collective behavior can reverse individual behavior, illustrating top-down control.
• Cells hetero-grafted from tissue in one phase of the segmentation clock into a different phase synchronize to the host phase (Horikawa et al. 2006)finding0.738
  Demonstrates that the clock phase is collectively determined; individual cells entrain to the local collective rhythm.
• In embryological development, chemistry and cell migrations are mechanisms that do the work but are simply not the principal thing going on — the fifteen properties and their unfolding are.claim0.733
  Alexander's interpretive priority claim distinguishing mechanistic substrate from the morphogenetic principle at work
• Cell fragments reverse taxis direction relative to intact cellsfinding0.730
  In electric fields: intact keratocytes migrate to cathode, but fragments of the same cells migrate to anode—collective behavior differs from component behavior.
• Ion channel-modified cells recruit neighbors to complete eye organogenesisfinding0.725
  Ectopic eyes induced by ion channel misexpression; if few cells injected, they recruit unmanipulated neighbors to produce normal-sized eyes—collective recruitment competency.
• Target morphology shifts occur despite the fact that all of the individual cells have unaltered normal genomes, showing that competent subunits can be pushed to implement diverse organism-scale goals by physiological signals.claim0.724
  Highlights the non-genetic control of large-scale anatomy.
• The cancer phenotype can be reverted by artificially managing the bioelectric connections between a cell and its neighbors.hypothesis0.718
  Predicts that restoring gap junctional coupling or appropriate Vmem can normalize oncogene-expressing cells.
• Cells maintain internal representations of correct anatomical structure (target morphology) that causally constrain growth, regeneration, and repair.claim0.715