finding
active
finding:cancer-phenotypes-can-be-suppressed-by-forcing-bioelectrical-connections-among-cells-overriding-oncogenic-mutations-chernet-levin-2013Cancer phenotypes can be suppressed by forcing bioelectrical connections among cells, overriding oncogenic mutations (Chernet & Levin 2013).
Shows that restoring bioelectric cohesion can override single-cell goals.
Source paper
extracted_from(2023) · Watson, Richard · Levin, Michael
Neighborhood — ranked by edge-count
Claims (1)
claim
- Identifies bioelectric networks as the medium of basal cognition.
Findings (1)
finding
- Empirical demonstration that bioelectric network topology, not genetic state, determines whether cellular optimization occurs at single-cell (cancer) vs. organ level.
Related by similarity (8)
cosine ≥ 0.65 · no typed edgeEntities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.
- The cancer phenotype can be reverted by artificially managing the bioelectric connections between a cell and its neighbors.hypothesis0.901Predicts that restoring gap junctional coupling or appropriate Vmem can normalize oncogene-expressing cells.
- Co-injection of a hyperpolarizing ion channel with oncogene prevented tumor formation and restored normal tissue, showing bioelectric control over genetic state.
- Empirical finding in developmental biology that supports organismic individuality independent of genetics
- Empirical support for the cancer-as-cognitive-defect / cognitive light cone shrinkage hypothesis
- Proposes a non-toxic cancer treatment strategy.
- Interpretive claim about the meaning of Xenobot behaviors.
Restated by (1)
cosine ≥ 0.90Other entities that say roughly the same thing. May be merge candidates or independent restatements across papers.