A simple voltage state imposed on somatic cells can induce them to build a complete vertebrate eye.

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• Voltage-induced ectopic eye formation in tadpolesfinding0.811
• Misexpression of a single ion channel induces complete ectopic eye formation in gut endoderm of vertebrates.finding0.792
  Setting cells to an eye-like bioelectric prepattern via ion channel manipulation creates fully formed eyes in abnormal locations, where the master gene Pax6 is insufficient.
• Ion channel-modified cells recruit neighbors to complete eye organogenesisfinding0.770
  Ectopic eyes induced by ion channel misexpression; if few cells injected, they recruit unmanipulated neighbors to produce normal-sized eyes—collective recruitment competency.
• Ectopic Eye Formation via Bioelectric Signalingfinding0.769
  Misexpression of potassium channels in frog tadpole gut or tail induces formation of complete, functional eyes in ectopic locations; demonstrates that morphogenetic modules can be triggered by high-level bioelectric signals without specifying molecular details.
• When a subset of cells is given a morphogenetic goal (e.g., build an eye), they autonomously recruit unmodified neighbors to complete the structure, showing modular competency.claim0.766
  Principle of top-down control.
• Ectopic eyes formed in frog embryo tails still function; eye primordia cells succeed in forming an eye, optic nerve, and correct neural connections despite abnormal spatial context.finding0.760
• It is highly implausible that all sentient life in the universe achieves felt states using the neural circuitry underlying human Consciousness on earth.claim0.757
  Reinforcement of substrate independence: Earth-like neural circuits are unlikely to be the sole substrate.
• Ectopic eyes on tadpole tail provide functional vision despite connecting only to spinal cord or peripheral tissue.finding0.754
  Result from Blackiston & Levin 2013: sensory data from displaced eyes can be used for learned behavior without evolutionary adaptation.