General anesthesia works by blocking gap junctions, thereby disrupting the higher-level cognitive self.

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• General anesthesia works by blocking gap junctions, thereby dissolving the higher-level Self while leaving individual cells functional.claim0.941
  Suggests that the unified self emerges from bioelectrical network coherence, which can be reversibly disrupted.
• General anesthetics are gap junction blockers, consistent with the role of gap junctions in scaling consciousness.claim0.893
  Links anesthesia mechanism to the bioelectric binding model of higher-level Selves.
• General anesthetics block gap junctions across plants, Hydra, and humansfinding0.871
  Gap junction blockers induce loss of consciousness in diverse organisms, supporting the bioelectric network hypothesis of the Self.
• General anesthetics are gap junction blockers.finding0.863
  Gap junction blockers function as anesthetics across plants, Hydra, and humans, consistent with GJs being critical for high-level Self maintenance.
• Gap junction blockade as general anesthesiaconcept0.855
  The observation that gap junction blockers anesthetize diverse organisms, supporting the hypothesis that bioelectric networks implement the unified Self.
• If gap junction-mediated bioelectric networks implement the unified Self, then gap junction blockers should function as general anesthetics across biology.hypothesis0.816
  Already supported by data in plants, Hydra, and humans, but broader cross-species testing is predicted.
• Gap junctions provide a dynamic that massively augments cooperative interactions and scales cognitive boundary.claim0.777
  Explains the biological mechanism for cognitive scaling.
• general anesthesiaconcept0.751
  Model system for mind rebooting after bioelectric network disruption.