finding

active

finding:individual-neural-crest-or-rhombomere-cells-lose-memory-of-past-inductive-cues-and-adopt-neighbors-expression-grafted-collectives-maintain-original-identity-trainor-and-krumlauf-2000

Individual neural crest or rhombomere cells lose memory of past inductive cues and adopt neighbors' expression; grafted collectives maintain original identity (Trainor and Krumlauf 2000)

Collectives have extended temporal perceptual fields, maintaining positional memory that single cells lose.

Source paper

extracted_from

Collective intelligence: A unifying concept for integrating biology across scales and substrates

(2024) · Patrick McMillen · Michael Levin

Neighborhood — ranked by edge-count

Communities (3)

community

Bioelectric morphogenesis & anatomical intelligence
members_of
Levin-led research showing bioelectric signals encode and control anatomical goal states in living systems.
Distributed biological agency and morphogenetic learning
members_of
Non-neural and neural tissues exhibit autonomous learning and goal-directed behavior in closed-loop systems, from cultured neurons to bioelectric collectives, challenging centralized brain-centric models of cognition.
Neural crest collective identity plasticity
members_of
Grafted neural crest collectives maintain Hox identity while isolated cells adopt host neighbors' expression.

Frameworks (1)

framework

Perceptual Field Model
supports
Model introduced in Figure 2 explaining how collective intelligence expands the spatiotemporal perceptual field of a group beyond any individual member's capacity.

Related by similarity (8)

cosine ≥ 0.65 · no typed edge

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

Grafted neural crest cell collectives maintain original Hox gene expression, while individual cells adopt neighbors' expression (Trainor and Krumlauf 2000)finding0.850
Collectives have increased positional memory and resist environmental induction, demonstrating expanded perceptual field in time dimension.
The neural crest acts as an intelligently migrating collective that can alter individual cell behavior to achieve target morphology.claim0.847
Specific claim illustrating collective intelligence in a well-studied embryonic system.
The remarkable ability of neurons to unify toward a centralized self is an evolutionary pivot of far earlier cell communication strategies that first solved problems in navigating anatomical morphospace.hypothesis0.786
Proposes an evolutionary trajectory linking morphogenesis to neural cognition.
Memories persist through complete brain remodeling during metamorphosis by transferring and remapping onto newly-constructed neural tissue.hypothesis0.781
Proposed mechanism explaining behavioral continuity in insects undergoing radical morphogenesis.
Memories are not immutable markers of identity; they can be transferred between individuals and remapped onto new substrates.claim0.771
Evidence from planarian tail fragment training and metamorphosis suggests memory is substrate-independent process.
Mouse neural crest cells grafted into chicken embryos successfully form teeth (Mitsiadis et al. 2003)finding0.769
Neural crest collective navigates a foreign embryonic environment to achieve its morphogenetic goal.
Target morphology shifts occur despite the fact that all of the individual cells have unaltered normal genomes, showing that competent subunits can be pushed to implement diverse organism-scale goals by physiological signals.claim0.769
Highlights the non-genetic control of large-scale anatomy.
Cells maintain internal representations of correct anatomical structure (target morphology) that causally constrain growth, regeneration, and repair.claim0.767