Grafted neural crest cell collectives maintain original Hox gene expression, while individual cells adopt neighbors' expression (Trainor and Krumlauf 2000)

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

• Individual neural crest or rhombomere cells lose memory of past inductive cues and adopt neighbors' expression; grafted collectives maintain original identity (Trainor and Krumlauf 2000)finding0.850
  Collectives have extended temporal perceptual fields, maintaining positional memory that single cells lose.
• Mouse neural crest cells grafted into chicken embryos successfully form teeth (Mitsiadis et al. 2003)finding0.788
  Neural crest collective navigates a foreign embryonic environment to achieve its morphogenetic goal.
• Target morphology shifts occur despite the fact that all of the individual cells have unaltered normal genomes, showing that competent subunits can be pushed to implement diverse organism-scale goals by physiological signals.claim0.767
  Highlights the non-genetic control of large-scale anatomy.
• Neural Crest Cellsconcept0.758
  Cell population that migrates throughout the body as an intelligently coordinating collective, achieving target locations through problem-solving in embryonic space.
• Cells exhibit generalization in physiological space, recognizing novel stressors as members of familiar classes to deploy transcriptional solutions.hypothesis0.756
  Predicts that cells can categorize perturbations and mount appropriate, not just hardwired, responses.
• The remarkable ability of neurons to unify toward a centralized self is an evolutionary pivot of far earlier cell communication strategies that first solved problems in navigating anatomical morphospace.hypothesis0.752
  Proposes an evolutionary trajectory linking morphogenesis to neural cognition.
• Organismic individuality can be separated from genetics: integration and collective action occur in non-neural systems.finding0.751
  Empirical findings from developmental biology (Manicka & Levin, Lyon et al.) supporting mechanistic basis for individuality independent of genetic determination.
• Most of Crump et al.'s other criteria are met by non-neural morphogenetic agents via a simple pivot of terms to 'electrically active cell'.claim0.750
  Generalization of the criteria beyond neurons.