H+ pump activation induces full tadpole tail regeneration

A transient proton pump activation triggers an entire regenerative cascade, demonstrating top-down control of morphogenesis.

Source paper

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Technological Approach to Mind Everywhere: An Experimentally-Grounded Framework for Understanding Diverse Bodies and Minds

(2022) · Michael Levin

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Bioelectric morphogenesis & anatomical intelligence
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Levin-led research showing bioelectric signals encode and control anatomical goal states in living systems.
Bioelectric code and anatomical goal-setting
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Xenopus studies showing ion channel patterns direct cell collectives toward specific anatomical outcomes independent of genetic or positional cues, led by Michael Levin.
Bioelectric signaling in morphogenesis
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Xenopus tadpole studies demonstrating how ion channel activity and bioelectric patterns control body plan formation independent of genetics.

Related by similarity (8)

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Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

V-ATPase proton pump can be functionally replaced by a yeast proton pump with no sequence homology to restore bioelectric state and tail regeneration.finding0.741
From Adams et al. 2007; shows bioelectric state is a coarse-grained control parameter, not tied to specific gene products.
Tadpoles with eyes transplanted to tail location perform visual learning tasks normally despite altered sensory anatomy.finding0.728
Evidence of neural plasticity; demonstrates mind's independence from specific body layout.
Tadpoles with ectopic eyes on their tails can see out of them, demonstrating radical functional plasticity without evolutionary adaptation.claim0.728
Example of innate problem-solving capacity.
Tadpoles with ectopic eyes on tail can see and integrate sensory input from aberrant locationfinding0.727
Demonstrates neural plasticity: brain adapts behavioral programs to sensory input from abnormal anatomical locations within single organism lifetime.
Voltage-induced ectopic eye formation in tadpolesfinding0.723
Ectopic eyes on tadpole tails support visual learning despite connecting to the spinal cord.finding0.718
From Blackiston & Levin (2013), shows plasticity of brain and body.
Ectopic eyes on tadpole tail provide functional vision despite connecting only to spinal cord or peripheral tissue.finding0.708
Result from Blackiston & Levin 2013: sensory data from displaced eyes can be used for learned behavior without evolutionary adaptation.
Tadpoles with ectopic eyes on tails can see and learn effectively in visual assays.finding0.707
Blackiston & Levin 2013 finding showing plasticity of sensorimotor integration.