Carcinogenesis illustrates failure of SCI loop integration when cells revert to unicellular selves and detach from collective morphogenetic goals.

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

• Cancer can be seen as a breakdown of the binding process that scales Selves, with cells reverting to unicellular goals.claim0.821
  Oncogene-induced gap junction closure shrinks the cognitive boundary of cells.
• Cancer is a breakdown of the multiscale binding, leading cells to revert to unicellular goals.hypothesis0.785
  Gap junction closure makes cells selfish, shrink their cognitive boundary; restoring Vmem can normalize.
• Cancer is a breakdown of the collective intelligence of tissues, a shrinking of the Self boundary due to gap junction closure.claim0.779
  Frames metastasis as cells reverting to unicellular goals, treatable by restoring bioelectric connectivity.
• Suppression of cancer phenotypes despite strong oncogenic mutations via forced bioelectrical connections among cells, overriding single-cell goals with morphogenetic ones.finding0.774
  Empirical demonstration that bioelectric network topology, not genetic state, determines whether cellular optimization occurs at single-cell (cancer) vs. organ level.
• Disruptions in cells' ability to join into a cohesive information-processing network via oncogenes and other factors correlate with cancer developmentfinding0.769
  Empirical support for the cancer-as-cognitive-defect / cognitive light cone shrinkage hypothesis
• If cancer represents a shrinkage of the cognitive light cone, then interventions that restore cellular participation in tissue-level information-processing networks should suppress cancer progression.hypothesis0.768
  Implicit predictive hypothesis from the cancer-as-cognitive-defect claim, with experimental implications for regenerative medicine
• Cancerous growth can be induced by disruption of electrical coordination signals and reversed by re-establishing them, without genetic changes (Levin 2021a)finding0.766
  Empirical finding in developmental biology that supports organismic individuality independent of genetics
• Morphogenesis operates through multiscale autopoietic processes in which every cell is simultaneously an environment for others, enabling coherent organism formation without predetermined configuration.finding0.765