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question:what-is-the-relationship-between-the-genome-and-anatomy-and-what-mechanisms-allow-biology-to-exhibit-robustness-and-plasticity-simultaneously

What is the relationship between the genome and anatomy, and what mechanisms allow biology to exhibit robustness and plasticity simultaneously?

Driving question for the research program.

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Endless forms most beautiful 2.0: teleonomy and the bioengineering of chimaeric and synthetic organisms

(2023) · Clawson, Wesley P. · Levin, Michael

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Claims (1)

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Significant gaps exist in our understanding of the origin of anatomical novelty, of the relationship between genome and form, and of strategies for control of large-scale structure and function.
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Author assertion about current knowledge gaps.

Related by similarity (8)

cosine ≥ 0.65 · no typed edge

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

What Mechanisms Allow Biology To Exhibit Robustness Andquestion0.830
How do organisms achieve robustness and plasticity simultaneously in novel circumstances?question0.816
Core question motivating bioengineering studies: how can biological systems adapt to unexpected perturbations while maintaining coherence?
What Is The Relationship Between The Genome Andquestion0.815
Biology's robustness, open-endedness, evolvability, and unique complexity likely depend on the fact that evolution works with an agential material.claim0.807
Central claim linking life's properties to the inherent competencies of its material substrate.
What Is The Relationship Between Genome And Functionalquestion0.805
Robustness in morphogenesis is achieved through plasticity and multiscale problem-solving, not hardwired repeatability.hypothesis0.804
Developmental robustness across perturbations arises from the cellular competency to reach the same goal by different means, not from fixed local rules; higher-order robustness.
The genome does not merely specify chemical structures to be assembled but also specifies complex patterns of interaction between molecular structures required to produce controlled behaviours of the individual organism.claim0.794
An extension of the genetic code concept: it encodes developmental and behavioural control, not just static form.
The genome contains a latent wholeness — capable of generating the wholeness of the organism — which itself evolves through structure-preserving transformations analogous to direct wholeness unfolding.claim0.783
Alexander's extension of unfolding wholeness to evolutionary processes where the evolving entity is the genetic structure rather than the organism's form directly

Cross-corpus bridges (9)

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What is the relationship between genome, software that produces bodies and behavior, and adaptive ends?questions/what-is-the-relationship-between-genome-software-that.md0.789
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Baldwin Effect Modelframeworks/baldwin-effect.md0.782