claim

active

claim:significant-gaps-exist-in-our-understanding-of-the-origin-of-anatomical-novelty-of-the-relationship-between-genome-and-form-and-of-strategies-for-control-of-large-scale-structure-and-function

Significant gaps exist in our understanding of the origin of anatomical novelty, of the relationship between genome and form, and of strategies for control of large-scale structure and function.

Author assertion about current knowledge gaps.

Source paper

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Endless forms most beautiful 2.0: teleonomy and the bioengineering of chimaeric and synthetic organisms

(2023) · Clawson, Wesley P. · Levin, Michael

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Communities (2)

community

Causal emergence in biological systems
members_of
Examines how macro-scale causal power exceeds micro-scale in living and learning systems.
Hierarchical emergence through nested centers and constraints
members_of
Alexander's 15 properties framework applied to evolutionary transitions, self-organization, and morphological design across scales using constraint-based emergence mechanisms.

Questions (1)

question

What is the relationship between the genome and anatomy, and what mechanisms allow biology to exhibit robustness and plasticity simultaneously?
gates
Driving question for the research program.

Related by similarity (8)

cosine ≥ 0.65 · no typed edge

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

The complex nature of functional relationships between component parts begins to look less like the product of selection at the system level, and more like the source of evolutionary individuality.claim0.782
Inverts the causal arrow: relationships produce individuality, not vice versa.
The genome does not merely specify chemical structures to be assembled but also specifies complex patterns of interaction between molecular structures required to produce controlled behaviours of the individual organism.claim0.780
An extension of the genetic code concept: it encodes developmental and behavioural control, not just static form.
The genome contains a latent wholeness — capable of generating the wholeness of the organism — which itself evolves through structure-preserving transformations analogous to direct wholeness unfolding.claim0.779
Alexander's extension of unfolding wholeness to evolutionary processes where the evolving entity is the genetic structure rather than the organism's form directly
The apparent mysteries of embryological morphogenesis may be more easily understandable when we consider that evolution from time t to t+1 is governed by strengthening centers while preserving and enhancing as much structure as possible.hypothesis0.779
Alexander's predictive hypothesis that the principle of unfolding wholeness will provide new explanatory leverage for embryology
Biology's robustness, open-endedness, evolvability, and unique complexity likely depend on the fact that evolution works with an agential material.claim0.779
Central claim linking life's properties to the inherent competencies of its material substrate.
Origin of Anatomical Noveltyquestion0.777
The creation of morphological novelty, biological invention, artistic creation, architectural invention ... may all be understood as products of a relatively simple process of intensifying existing latent centers.claim0.775
Claim that the emergence of new forms, often considered mysterious, is explainable through repeated intensification of latent structure.
Many recent discussions of AI, and its impact on individuals and on society, are importantly incomplete because they neglect Diverse Intelligence, synthetic morphology, and developmental biology.claim0.773
Central thesis of the paper — the framing premise from which all other arguments follow

Cross-corpus bridges (6)

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External markdown files that talk about the same concept as this entity.

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What is the relationship between the genome and anatomy, and what mechanisms allow biology to exhibit robustness and plasticity simultaneously?questions/what-is-the-relationship-between-the-genome-and.md0.831
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What determines the shape of an organism, and what is the relationship between the genome and anatomy?questions/what-determines-the-shape-of-an-organism-and.md0.824
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How can organisms with extremely variable or messy genomes (like planaria) exhibit superior morphological control compared to organisms with stable genomes?questions/how-can-organisms-with-extremely-variable-or-messy.md0.809
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How do we explain the ubiquitous presence of novel capabilities in living things for which no direct selection forces are plausible?questions/how-do-we-explain-the-ubiquitous-presence-of.md0.804
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How do organisms solve the problem of specifying and maintaining complex anatomical structures?questions/how-do-organisms-solve-the-problem-of-specifying.md0.802
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To what extent does biological form derive from genetics versus from active interpretation of genetic resources?questions/to-what-extent-does-biological-form-derive-from.md0.786