hypothesis
active
prediction:bioelectric-prepatterns-instructively-determine-target-morphology-and-organ-inductionBioelectric prepatterns instructively determine target morphology and organ induction.
Source paper
extracted_from(2023) · Levin, Michael
Related by similarity (8)
cosine ≥ 0.65 · no typed edgeEntities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.
- Bioelectric prepatterns encode pattern memories that guide morphogenesis toward target morphologies.hypothesis0.857Tested in planaria and frog face development; predicts similar mechanisms in other systems.
- A prespecified target morphology encoded as an anatomical setpoint; paper uses the 'electric face' from frog embryogenesis as a model system.
- Manipulating bioelectric states can reprogram target morphology without changing genetics.hypothesis0.802Demonstrated by inducing two-headed planaria via ion channel drugs; predicts cancer normalization.
Cross-corpus bridges (3)
same_concept_as · Nomic cosineExternal markdown files that talk about the same concept as this entity.
- aboutblank_kbHow are bioelectric prepatterns used to specify organ identity and location during development?questions/how-are-bioelectric-prepatterns-used-to-specify-organ.md0.852
- aboutblank_kbBioelectric Prepatternconcepts/biology/bioelectric-prepattern.md0.841
- aboutblank_kbHow is the target morphology or homeostatic setpoint represented and stored in biological systems?questions/how-is-the-target-morphology-or-homeostatic-setpoint.md0.800