hypothesis
active
hypothesis:bioelectric-prepatterns-encode-pattern-memories-that-guide-morphogenesis-toward-target-morphologiesBioelectric prepatterns encode pattern memories that guide morphogenesis toward target morphologies.
Tested in planaria and frog face development; predicts similar mechanisms in other systems.
Source paper
extracted_from(2022) · Michael Levin
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Concepts (1)
concept
- BioelectricityaboutProposed 'cognitive glue' common to both neural and developmental collective intelligence; implemented by ion channels and electrical synapses.
Questions (1)
question
- Specific question about the mechanism of anatomical homeostasis.
Related by similarity (8)
cosine ≥ 0.65 · no typed edgeEntities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.
- Planarian head number can be permanently altered by re-writing bioelectric prepatterns.
- Asserts that evolution exploits a software-like layer for anatomical form, enabling rapid morphological change.
- Testable by computational modeling and experimental perturbation of specific bioelectric circuits.
- Testable prediction that insights from developmental bioelectricity can illuminate behavioral cognition and vice versa; grounds portability of neuroscience tools across tissue types.
- Hypothesis that bioelectric voltage patterns encode morphogenetic information and persist across regeneration, guiding form despite genetic variability.
Cross-corpus bridges (8)
same_concept_as · Nomic cosineExternal markdown files that talk about the same concept as this entity.
- aboutblank_kbBioelectric Prepatternconcepts/biology/bioelectric-prepattern.md0.892
- aboutblank_kbHow are bioelectric prepatterns used to specify organ identity and location during development?questions/how-are-bioelectric-prepatterns-used-to-specify-organ.md0.850
- aboutblank_kbHow do bioelectric networks store and manipulate morphogenetic memories independent of genetic sequence?questions/how-do-bioelectric-networks-store-and-manipulate-morphogenetic.md0.846
- aboutblank_kbHow do bioelectric signals enable cells to coordinate morphogenetic patterning independent of genetic instructions?questions/how-do-bioelectric-signals-enable-cells-to-coordinate.md0.838
- aboutblank_kbMorphogenetic Pattern Memoriesconcepts/cognitive/morphogenetic-pattern-memories.md0.835
- aboutblank_kbWhat are the detailed mechanisms by which bioelectric patterns scale up from subcellular to tissue and organ levels?questions/what-are-the-detailed-mechanisms-by-which-bioelectric.md0.816
- aboutblank_kbPattern Memoryconcepts/biology/pattern-memory.md0.815
- aboutblank_kbCounterfactual Representationconcepts/cognitive/counterfactual-representation.md0.782