Gastruloids derived from embryonic stem cells arrive at a segmented target morphology despite very different ontogenic history (Veenvliet et al. 2020, van den Brink et al. 2020)

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

• Target morphology shifts occur despite the fact that all of the individual cells have unaltered normal genomes, showing that competent subunits can be pushed to implement diverse organism-scale goals by physiological signals.claim0.784
  Highlights the non-genetic control of large-scale anatomy.
• The larger task of making these processes genuinely morphogenetic so that they generate deeper and more coherent living structure—still lies on the horizon.claim0.755
• The apparent mysteries of embryological morphogenesis may be more easily understandable when we consider that evolution from time t to t+1 is governed by strengthening centers while preserving and enhancing as much structure as possible.hypothesis0.753
  Alexander's predictive hypothesis that the principle of unfolding wholeness will provide new explanatory leverage for embryology
• Cells maintain internal representations of correct anatomical structure (target morphology) that causally constrain growth, regeneration, and repair.claim0.752
• Cells hetero-grafted from tissue in one phase of the segmentation clock into a different phase synchronize to the host phase (Horikawa et al. 2006)finding0.750
  Demonstrates that the clock phase is collectively determined; individual cells entrain to the local collective rhythm.
• Morphogenesis guarantees that coherent wholes will form even while the piecemeal process allows each place to be unique.claim0.750
  Key property of morphogenetic process: it produces both unity and diversity simultaneously.
• The boundary between evolved and designed agents is becoming blurred through biorobotics and synthetic morphology.claim0.749
• The formation of centers is guided by generic patterns which play the role of genes.claim0.749
  Analogy to biology, placing pattern languages as the genetic code for living built environments.