finding
active
finding:artificially-induced-frog-leg-regeneration-follows-a-non-developmental-path-like-a-plant-to-produce-a-normal-limbArtificially induced frog leg regeneration follows a non-developmental path (like a plant) to produce a normal limb.
Frog legs regenerated after specific induction did not form a paddle with interdigital apoptosis but grew digits from a central core, reaching correct final form via atypical intermediate states.
Source paper
extracted_from(2022) · Levin, Michael
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Communities (4)
community
- Levin-led research showing bioelectric signals encode and control anatomical goal states in living systems.
- Bioelectric morphogenesis & memorymembers_ofMichael Levin's research on bioelectric signaling controlling anatomical goals, regeneration, and cancer.
- Xenopus studies showing ion channel patterns direct cell collectives toward specific anatomical outcomes independent of genetic or positional cues, led by Michael Levin.
- Studies how organisms achieve correct anatomy despite disrupted cell organization, using xenopus models to examine non-genetic developmental constraints.
Concepts (1)
concept
- Anatomical HomeostasissupportsAbility of organisms to adjust anatomy despite injury or rearrangement; demonstrates collective problem-solving in morphospace.
Related by similarity (8)
cosine ≥ 0.65 · no typed edgeEntities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.
- Indicates that prior experience can alter morphogenetic capacity.
- Embryological finding showing the specific mechanism — insertion of new local symmetries — by which wholeness is preserved and extended in biological development
- Salamander limbs regenerate missing parts precisely and stop when target morphology is reached, demonstrating goal-directed morphogenesis.
- Evidence of morphogenetic problem-solving and anatomical homeostasis across serious perturbations; demonstrates collective intelligence in development.
- Biological example of anatomical homeostasis: amputated limb regrows and knows when to stop, demonstrating error-minimization and setpoint-seeking behavior.
- Empirical example of regulative development: when craniofacial organs are positioned abnormally, they reposition via non-natural paths until correct frog face is achieved.
- Tadpoles with scrambled craniofacial organ positions (Picasso tadpoles) develop into largely normal frogs.finding0.729When eyes, nostrils, and jaws were mispositioned, they moved via novel trajectories and stopped upon reaching correct frog face positions, demonstrating anatomical homeostasis.