concept

active

concept:wiping-of-ownership-information-by-gap-junctions

Wiping of ownership information by gap junctions

Gap junctional coupling erases origin metadata of signals, causing cells to experience false physiological memories, binding them into a larger Self.

Neighborhood — ranked by edge-count

Concepts (1)

concept

Gap Junctions
subtype_ofsupports
Cellular connections that enable bioelectric communication; form bioelectric networks underlying morphogenetic control and can be manipulated experimentally via molecular reagents.

Findings (1)

finding

Gap junction blockade stochastically induces heads of other planarian species in genetically wild-type worms.
supports
Temporary disruption of gap junctions causes planaria to reconstruct heads appropriate to other species, revealing latent morphospace attractors.

Related by similarity (8)

cosine ≥ 0.65 · no typed edge

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

Gap junctions provide an 'owner wiping property' for signaling molecules, leading to partial erasure of individual identity for cells in a network and enabling a higher-order emergent collective.claim0.798
Mechanistic claim for how collectives scale.
How Do Gap Junctions Enable Partial Erasure Ofquestion0.768
Gap junctional coupling wipes ownership information on signaling molecules, enabling the formation of multicellular Selves.claim0.762
Because cells cannot distinguish internally generated signals from those arriving through GJs, they share memories and bind into a larger agent.
gap junction manipulationmethod0.742
Using drugs or genetic tools to open/close gap junctions and probe bioelectric networks in development.
Gap junctions enable 'mind meld' through impossibility of information hidingfinding0.713
Gap junction blockademethod0.693
Pharmacological blockade of gap junctional communication used to alter morphological pattern memory and scaling.
Genetic, chemical, and optical manipulation of ion channels and gap junctionsmethod0.692
Gap junctional coupling partially erases informational boundaries between cells, enabling the scaling of the Self to tissue- and organ-level goals.claim0.682
Proposes a mechanism for how merging physiological states via gap junctions creates a new, larger cognitive agent.