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claim:gap-junctional-coupling-wipes-ownership-information-on-signaling-molecules-enabling-the-formation-of-multicellular-selves

Gap junctional coupling wipes ownership information on signaling molecules, enabling the formation of multicellular Selves.

Because cells cannot distinguish internally generated signals from those arriving through GJs, they share memories and bind into a larger agent.

Source paper

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Technological Approach to Mind Everywhere: An Experimentally-Grounded Framework for Understanding Diverse Bodies and Minds

(2022) · Levin, Michael

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Communities (3)

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Bioelectric memory & morphogenetic identity
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Gap junctions and bioelectric signals encode body-plan and memory patterns across radical biological transformation.
Gap junctions & collective morphogenetic selfhood
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Levin-framework linking gap junction bioelectricity to cancer, planaria, and scaling of cellular Selves.
Gap junctions as consciousness scaling mechanism
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Explores how gap junction coupling enables multicellular self-organization and consciousness across species, with anesthetics as empirical probes of this bioelectric integration.

Related by similarity (8)

cosine ≥ 0.65 · no typed edge

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

Gap junctions provide an 'owner wiping property' for signaling molecules, leading to partial erasure of individual identity for cells in a network and enabling a higher-order emergent collective.claim0.895
Mechanistic claim for how collectives scale.
Gap junctional coupling partially erases informational boundaries between cells, enabling the scaling of the Self to tissue- and organ-level goals.claim0.892
Proposes a mechanism for how merging physiological states via gap junctions creates a new, larger cognitive agent.
Gap junctional coupling scales up the cognitive Self by partially erasing informational boundaries between cells.hypothesis0.869
A mechanistic model: loss of ownership information on internal signals fuses cells into larger agents.
Gap junctions provide a dynamic that massively augments cooperative interactions and scales cognitive boundary.claim0.833
Explains the biological mechanism for cognitive scaling.
If gap junction-mediated bioelectric networks implement the unified Self, then gap junction blockers should function as general anesthetics across biology.hypothesis0.803
Already supported by data in plants, Hydra, and humans, but broader cross-species testing is predicted.
Gap junctions enable 'mind meld' through impossibility of information hidingfinding0.793
Bioelectric networks formed by gap junctions scale cell-level homeostatic loops into organ-level anatomical homeostasis.hypothesis0.788
Proposed mechanism for scaling of goal-directed activity from cells to tissues.
The remarkable ability of neurons to unify toward a centralized self is an evolutionary pivot of far earlier cell communication strategies that first solved problems in navigating anatomical morphospace.hypothesis0.777
Proposes an evolutionary trajectory linking morphogenesis to neural cognition.

Cross-corpus bridges (4)

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External markdown files that talk about the same concept as this entity.

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How do gap junctions enable partial erasure of individual cellular identity and support emergence of larger-scale collective agents?questions/how-do-gap-junctions-enable-partial-erasure-of.md0.833
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How do individual cell-level goals scale up into coherent organism-level Selves without central control?questions/how-do-individual-celllevel-goals-scale-up-into.md0.813
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Gap Junctionsconcepts/biology/gap-junctions.md0.810
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Can gap junctional connectivity be used as a therapeutic target to reverse cancer phenotypes?questions/can-gap-junctional-connectivity-be-used-as-a.md0.802