hypothesis
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hypothesis:gap-junctional-coupling-scales-up-the-cognitive-self-by-partially-erasing-informational-boundaries-between-cellsGap junctional coupling scales up the cognitive Self by partially erasing informational boundaries between cells.
A mechanistic model: loss of ownership information on internal signals fuses cells into larger agents.
Source paper
extracted_from(2022) · Michael Levin
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Concepts (1)
concept
- Gap JunctionsaboutCellular connections that enable bioelectric communication; form bioelectric networks underlying morphogenetic control and can be manipulated experimentally via molecular reagents.
Related by similarity (8)
cosine ≥ 0.65 · no typed edgeEntities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.
- Proposes a mechanism for how merging physiological states via gap junctions creates a new, larger cognitive agent.
- Explains the biological mechanism for cognitive scaling.
- Because cells cannot distinguish internally generated signals from those arriving through GJs, they share memories and bind into a larger agent.
- Mechanistic claim for how collectives scale.
- Frames metastasis as cells reverting to unicellular goals, treatable by restoring bioelectric connectivity.
- Proposes an evolutionary trajectory linking morphogenesis to neural cognition.
- Bioelectric networks formed by gap junctions scale cell-level homeostatic loops into organ-level anatomical homeostasis.hypothesis0.779Proposed mechanism for scaling of goal-directed activity from cells to tissues.
Cross-corpus bridges (4)
same_concept_as · Nomic cosineExternal markdown files that talk about the same concept as this entity.
- aboutblank_kbHow do gap junctions enable partial erasure of individual cellular identity and support emergence of larger-scale collective agents?questions/how-do-gap-junctions-enable-partial-erasure-of.md0.818
- aboutblank_kbHow do individual cell-level goals scale up into coherent organism-level Selves without central control?questions/how-do-individual-celllevel-goals-scale-up-into.md0.814
- aboutblank_kbScaling Of The Selfconcepts/interdisciplinary/scaling-of-the-self.md0.801
- aboutblank_kbCan gap junction connectivity directly specify Self boundaries and determine what agents experience as stress or suffering?questions/can-gap-junction-connectivity-directly-specify-self-boundaries.md0.799