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leiden_hybrid_concepts
label: haiku
community:leiden_hybrid_concepts-run4-c12-c3Bioelectric code and morphological memory in planarians
Studies of how ion channel bioelectric patterns encode anatomical information independent of genetics, enabling regeneration fidelity and behavioral memory preservation across complete body regeneration.
7 members. Each node is clickable.
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Drawn from 5 sources
The papers/notes whose extracted claims & findings make up this cluster.
- Technological Approach to Mind Everywhere: An Experimentally-Grounded Framework for Understanding Diverse Bodies and Minds3 members
- Endless forms most beautiful 2.0: teleonomy and the bioengineering of chimaeric and synthetic organisms1 member
- Technological Approach to Mind Everywhere: An Experimentally-Grounded Framework for Understanding Diverse Bodies and Minds1 member
- Collective intelligence: A unifying concept for integrating biology across scales and substrates1 member
- Bioelectric networks: the cognitive glue enabling evolutionary scaling from physiology to mind1 member
Bridges (2)
Other communities that share members with this one — cross-cutting threads or papers that sit at the seam between two themes.
Findings (7)
- Memory retention in planarian tail fragment regeneration
- Modification of cell-cell communication during planarian regeneration causes genetically-normal fragments to produce heads appropriate to other species (Emmons-Bell et al. 2015, Sullivan et al. 2016)Shows that morphological attractors can be switched via physiological cues, revealing the navigation of morphospace by collectives.
- Planaria exposed to barium regenerate heads insensitive to barium via limited transcriptional changesDespite no evolutionary exposure to barium, planaria solve the physiological stressor by regulating a small set of genes, demonstrating problem-solving in transcriptional space.
- Planaria retain conditioned responses after complete brain regenerationWorms trained before decapitation re-acquire the memory after regenerating a new brain, showing transfer of information across tissues.
- Planarian fragments regenerate with near 100% fidelity of anatomical structurePlanarians cut into pieces regenerate precisely what is missing and re-scale tissue to form complete worms.
- Planarian Two-Headed Regeneration via Bioelectric Circuit Rewriting
- Planarians maintain high regenerative fidelity despite genetic heterogeneity and chromosomal variation