Damage to insular cortex impairs both interoceptive accuracy and subjective feeling

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• Meta-analysis demonstrates negative affect, physical pain, and cognitive control activate an overlapping region of the anterior midcingulate cortex functioning as a domain-general evaluative hubfinding0.725
  Meta-analytic convergence supporting inseparability of evaluative and affective processing in ACC
• A sensory anomaly (sticker mismatch) can itself become an intrinsic drive for action under active inference, even without external rewardclaim0.717
  Core mechanism claim linking mismatch detection to behavior through EFE minimization
• Impulsivity→interest steering: probe entropy increases (LMM slope=0.024, p=2.30×10⁻⁴) but report entropy does not (p=0.11)finding0.712
  Evidence of a bottleneck between richer internal variation and final report distribution in impulsivity→interest condition
• "[W]e must confess that perception, and what depends upon it, is inexplicable in terms of mechanical reasons... when inspecting its interior, we will find only parts that push one another, and we will never find anything to explain a perception."quote0.705
  Canonical illustration of the Hard Problem intuition that any functional/mechanical explanation faces an explanatory gap for perception
• Individual neural crest or rhombomere cells lose memory of past inductive cues and adopt neighbors' expression; grafted collectives maintain original identity (Trainor and Krumlauf 2000)finding0.703
  Collectives have extended temporal perceptual fields, maintaining positional memory that single cells lose.
• The effect of alignment map ϕ complexity on IIA in causal abstraction is an analogue of the probing complexity–accuracy trade-offclaim0.703
  Authors connect their finding to the prior probing literature debate
• The gradual reconvergence of aT and aF activation clusters in final layers reflects the model's internal conflict or moral dilemma during deceptive behavior generationclaim0.702
  Interpretive claim attributing representational pattern to internal model state during threat-based deception
• fMRI showed increased right hemisphere anterior superior temporal gyrus activity for insight solutions, with EEG showing a gamma-band burst in the same region beginning 0.3s prior to insight (Jung-Beeman et al., 2004).finding0.702
  Neural correlate of insight used to support prediction about early neural activity following structure learning