Quote: stress leak as signaling mechanism

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• Stress molecules leak from source cells and diffuse to neighbors, making shared stress a conserved signal for cooperation.claim0.784
  Central hypothesis that stress sharing enables cooperation without explicit altruism by making individual problems collective.
• Cells should leak molecules such as HSP90 extracellularly as a stress sharing mechanism.claim0.771
  Prediction for in-vivo biology from the model.
• Stressed cells leak stress signals to neighbors, raising their plasticity and enabling them to create temporary passages (tunnels) for movement.hypothesis0.771
• Stress Response Mechanismconcept0.753
• Stress as the Glue of Agencyconcept0.753
  Stress is a systemic response to setpoint deviations that scales up homeostatic loops and binds subunits into a larger Self.
• Quote: stress as shared problemconcept0.752
• stress reservoirconcept0.752
  A finite capacity for stress in each individual; when full, functioning breaks down.
• Stress, as a systemic response to distance from setpoint states, serves as the glue of agency, binding subunits into higher Selves.claim0.744
  Stress propagation through gap junctions recruits distant cells to act cooperatively.