claim

active

claim:sequential-morphogenesis-causes-stress-to-fluctuate-over-the-course-of-development

Sequential morphogenesis causes stress to fluctuate over the course of development.

Observation from part-by-part target experiment.

Source paper

extracted_from

Stress sharing as cognitive glue for collective intelligences: A computational model of stress as a coordinator for morphogenesis

(2024) · Shreesha, Lakshwin · Levin, Michael

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Findings (1)

finding

In stress-sharing embryo, average stress reduced to zero at step 40 during sequential target morphogenesis; without-sharing stress settled at non-zero with <55 cells moving
supports
Shows stress sharing allows perfect formation of part-by-part target patterns.

Related by similarity (8)

cosine ≥ 0.65 · no typed edge

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

Sharing of stress between cells facilitates morphogenesis and increases robustness of morphogenetic outcomes.hypothesis0.839
Prior hypothesis tested in the paper; from Levin 2022.
Stress-sharing embryos achieve perfect sequential target patterns; non-sharing limited to <1% improvement.finding0.794
Stress-sharing embryos formed each sequential target with stress reducing to zero; non-sharing achieved only tiny improvements.
Morphogenesis is not simply an emergent result of local rules but has complex, multi-scale feedback mechanisms that implement teleonomy and problem-solving.claim0.788
Posits genuine goal-directedness in development.
Morphogenesis operates through multiscale autopoietic processes in which every cell is simultaneously an environment for others, enabling coherent organism formation without predetermined configuration.finding0.787
Knowledge of embryonic stress patterns does not enable deduction of the morphogenetic goal state; stress maps are private.claim0.784
An instance of privacy property in minimal agents.
By sharing stress with neighbors, one cell’s (or region’s) problem becomes everyone’s problem, leading to a higher willingness to adopt new configurations in which everyone’s free energy is lower (and thus, more optimal morphogenetic problem-solving).quote0.781
Encapsulates the core idea of stress sharing as collective cooperation.
Stress sharing will be favored by evolutionary processes.hypothesis0.780
Evolutionary fitness hypothesis tested in the GA.
What features of morphogenesis enable evolution to search a difficult space with pleiotropy, degeneracy, and redundancy so rapidly and effectively?question0.779
Core open problem: asks how cellular competency affords evolutionary speed and robustness despite the ruggedness of the genotype-phenotype mapping.