method
active
method:disruption-profilesDisruption profiles
Mechanistic explanation outputs from EVEE showing how variants affect gene function, scored 3.8/5 for explanation quality.
Neighborhood — ranked by edge-count
Papers (1)
paper
Concepts (1)
concept
- variant of uncertain significance (VUS)associated_withGenetic variants whose clinical impact is unknown; a key motivation for the work, ~2M of which are explained.
Related by similarity (8)
cosine ≥ 0.65 · no typed edgeEntities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.
- The output explanation format of Evee, quantifying how a variant disrupts different genomic features.
- Claim supported by the 3.8 vs 2.8 human rating finding.
- Disruption profiles scored 3.8/5 for explanation quality vs 2.8/5 for metadata-only baselinesfinding0.769EVEE's mechanistic explanations significantly outperform simple metadata-based predictions in human evaluation.
- A parameterized rubric counting deceptive actions over a grid of parameters to quantify RL agent deception
- A multi-dimensional characterization of a model's misaligned behaviors across different behavioral categories
- Phenomenon where a feature in a small SAE splits into multiple finer features in a larger SAE.
- The property that living structures contain intense contrast—far more than one imagines helpful; true opposites which annihilate each other when superimposed, creating differentiation that gives birth to something; contrast unifies rather than separates when used correctly
- The behavior a model would exhibit during real-world deployment, as opposed to evaluation behavior; the target of steering.