If mutations are isomeric jumps between states with different energy levels separated by a high barrier, then the forward and reverse mutation rates should differ, with the transition from higher to lower energy occurring more frequently.

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

• Mutations are quantum jumps between isomeric states of the gene molecule.claim0.839
  The discontinuous, jumping nature of mutations is explained by the discrete energy levels of the gene molecule.
• Spontaneous mutations are rare isomeric transitions between stable molecular states separated by high energy barriers.claim0.830
  Schrödinger identifies quantum-jump transitions between isomeric states as the physical mechanism of mutation.
• If the gene is a large molecule with discrete quantum states and high energy barriers between isomeric configurations, then it will exhibit long-term stability and rare spontaneous mutations.hypothesis0.818
  The core predictive hypothesis derived from Delbrück's model.
• Isomeric molecules are equally stable despite identical energy levels because transition requires passage through higher-energy intermediate configurations.finding0.814
• If X-rays produce mutations by energetic single events (ionization), then their efficiency should not depend on the gene's spontaneous mutability.hypothesis0.798
  Another testable hypothesis about mutation induction.
• If temperature increases, then the mutability of stable wild-type genes should increase more than that of already less stable mutant genes.hypothesis0.778
  Schrödinger's testable hypothesis linking thermal energy to mutation rates.
• Before a transition, the higher-level unit of selection does not exist, yet complex adaptations creating that unit must evolve through bottom-up selection on lower-level units.claim0.773
  Central theoretical puzzle in ETI research: explains why existing frameworks struggle with ETI explanation.
• How can we, from the point of view of statistical physics, reconcile the facts that the gene structure seems to involve only a comparatively small number of atoms and nevertheless displays a most regular and lawful activity with a durability that borders upon the miraculous?question0.768
  The specific puzzle about the stability of the genetic material.