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finding:bioelectric-coordination-creates-stochastic-concordance-in-melanocyte-fate-decisions-across-an-organism

Bioelectric coordination creates stochastic concordance in melanocyte fate decisions across an organism

Source paper

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Darwin's agential materials: evolutionary implications of multiscale competency in developmental biology

(2023) · Levin, Michael

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Communities (3)

community

Bioelectric morphogenesis & anatomical intelligence
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Levin-led research showing bioelectric signals encode and control anatomical goal states in living systems.
Bioelectric morphogenesis & memory
members_of
Michael Levin's research on bioelectric signaling controlling anatomical goals, regeneration, and cancer.
Bioelectric networks as morphogenetic cognition
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Membrane potential dynamics coordinate multicellular behavior, anatomical memory, and agency scaling across biological levels—studied via melanocyte fate, biofilm oscillations, and xenobotic morphology experiments (Levin et al. 2015–2023).

Concepts (1)

concept

Collective Intelligence
supports
Recognition that selves are composite systems of competent parts; all intelligences are higher-level selves made of cells or components.

Related by similarity (8)

cosine ≥ 0.65 · no typed edge

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

Bioelectric Control of Melanocyte Behaviorfinding0.799
Serotonergic signaling from instructor cells controls melanocyte proliferation and invasiveness in frog embryos; bioelectric perturbations produce stochastic organism-level outcomes (70% conversion) while maintaining cell-level concordance.
How Does Developmental Bioelectricity Enable Multicellular Coordination Andquestion0.793
Evolution pivoted bioelectric networks' control of spatial pattern during morphogenesis into nervous systems' control of temporal patterns during behavior.claim0.793
Hypothesis on evolutionary origin of behavioral intelligence from morphogenetic competencies.
Bioelectric networks scale cell computation into anatomical homeostasis and are a mechanism for evolving larger Selves.claim0.786
Developmental bioelectricity is proposed as a tractable entry point to understand the informational architecture of collective intelligence in morphogenesis.
Bioelectric states can serve as master regulators of organogenesis, bypassing the need to manipulate downstream genetic cascades.hypothesis0.781
Predicts that simple voltage changes can trigger complex modular morphogenetic programs, useful for regenerative medicine.
Developmental bioelectricity scales cell-level feedback into anatomical homeostasis.hypothesis0.781
Bioelectricity serves as a ‘cognitive glue’ common to collective and individual intelligence, binding cells into competent individuals in both behaviour and morphogenetic spaces.claim0.777
Identifies bioelectric networks as the medium of basal cognition.
Bioelectric networks scale agency across organizational levels by integrating homeostatic competencies of cells into emergent systems with larger cognitive light cones.claim0.777
Core thesis: bioelectric networks provide the mechanism by which single-cell homeostasis becomes organism-level agency through integration and feedback loops.

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same_concept_as · Nomic cosine

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What mechanisms enable cells to make coherent system-level decisions from stochastic individual events?questions/what-mechanisms-enable-cells-to-make-coherent-systemlevel.md0.829