claim

active

claim:if-intercellular-signalling-not-genes-is-the-cognitive-medium-of-a-morphogenetic-individual-it-should-be-possible-to-exploit-tools-of-neuroscience-to-read-interpret-and-re-write-its-information-content-for-predictive-control

If intercellular signalling (not genes) is the cognitive medium of a morphogenetic individual, it should be possible to exploit tools of neuroscience to read, interpret and re-write its information content for predictive control.

Strong prediction from basal cognition framework; validated in planaria and other species through bioelectric manipulation.

Source paper

extracted_from

The collective intelligence of evolution and development

(2023) · Watson, Richard · Levin, Michael

Neighborhood — ranked by edge-count

Findings (1)

finding

Transient bioelectrical modulation of body-wide pattern memory circuits in planaria can shift them from one-headed to persistent two-headed state, persisting through amputation rounds until reset with different manipulation.
supports
Experimental evidence that organism-scale goals can be rewritten through physiological signals without genetic modification; demonstrates bioelectricity as cognitive medium.

Communities (3)

community

Bioelectric morphogenesis & anatomical intelligence
members_of
Levin-led research showing bioelectric signals encode and control anatomical goal states in living systems.
Morphogenesis as collective basal cognition
members_of
Levin-influenced framework treating tissue-level morphogenesis as goal-directed, problem-solving intelligence via bioelectric signaling.
Bioelectric computation beyond neural systems
members_of
Using neuroscience tools to read and rewrite non-neural bioelectric signaling for morphogenetic control and predictive modeling.

Related by similarity (8)

cosine ≥ 0.65 · no typed edge

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

If intercellular signaling (not genes) is the cognitive medium of morphogenesis, then bioelectric signals can be read, interpreted, and rewritten to predictively control growth and form without genetic changes.hypothesis0.929
Predictive hypothesis validated in planarians and other species; enables therapeutic manipulation of morphogenetic targets.
Bioelectric signaling is the cognitive medium of morphogenetic collectives, analogous to neural synapses in individual brains.claim0.817
Morphogenesis constitutes basal cognition because it requires information integration and coordinated action characteristic of problem-solving in anatomical morphospace.claim0.807
The collective intelligence of tissues is sophisticated enough to be trainable via reinforcement learning for specific morphological outcomes.hypothesis0.798
Ongoing test prediction: tissues can associate stimuli with rewards to modify anatomy.
If morphogenesis and cognition share deep isomorphism, then significant overlap is predicted in genes involved in pattern regulation and memory/learning.hypothesis0.795
Bioinformatic prediction that ion channel, connexin, and neurotransmitter genes will appear in both developmental and cognitive contexts.
Morphogenetic physiology is the 'software' layer between genome and phenotypeclaim0.793
The remarkable ability of neurons to unify toward a centralized self is an evolutionary pivot of far earlier cell communication strategies that first solved problems in navigating anatomical morphospace.hypothesis0.792
Proposes an evolutionary trajectory linking morphogenesis to neural cognition.
Morphogenetic tissues can be trained via reinforcement learning for specific anatomical outcomes, bypassing the complexity of genomic editing.claim0.789
Proposes a biomedical strategy of controlling growth by exploiting the learning capacity of cellular collectives.

Cross-corpus bridges (9)

same_concept_as · Nomic cosine

External markdown files that talk about the same concept as this entity.

aboutblank_kb
How does bioelectric signaling serve as a cognitive substrate for morphogenesis and anatomical control?questions/how-does-bioelectric-signaling-serve-as-a-cognitive.md0.845
aboutblank_kb
Can electoral signals and information integration without genetic homogeneity maintain multicellular coordination and prevent cancer?questions/can-electoral-signals-and-information-integration-without-genetic.md0.833
aboutblank_kb
How can bioelectric signaling enable cells to pursue anatomical goals in morphospace despite genetic diversity?questions/how-can-bioelectric-signaling-enable-cells-to-pursue.md0.830
aboutblank_kb
How do morphogenetic systems make large-scale anatomical decisions through distributed cellular communication without centralized control?questions/how-do-morphogenetic-systems-make-largescale-anatomical-decisions.md0.826
aboutblank_kb
How do multicellular systems maintain coherent identity and solve problems collectively despite lacking central control?questions/how-do-multicellular-systems-maintain-coherent-identity-and.md0.816
aboutblank_kb
What are the mechanisms by which simple bioelectric signals trigger complex, context-appropriate morphogenetic responses that generate novel structures not anticipated by the signal itself?questions/what-are-the-mechanisms-by-which-simple-bioelectric.md0.811
aboutblank_kb
How do biological systems encode and recall anatomical target states independent of genetic specification?questions/how-do-biological-systems-encode-and-recall-anatomical.md0.799
aboutblank_kb
Can cells implement reverse central dogma—determining which genes to edit based on physiological state?questions/can-cells-implement-reverse-central-dogmadetermining-which-genes.md0.792
aboutblank_kb
How can we identify high-leverage intervention points in complex biological systems?questions/how-can-we-identify-highleverage-intervention-points-in.md0.780