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claim:genetic-information-must-encode-not-only-physical-forms-but-also-complex-self-modifying-control-mechanisms-for-behavior-and-development

Genetic information must encode not only physical forms but also complex self-modifying control mechanisms for behavior and development.

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2021-11-09_dorian_schrodinger-life.pdf_c3c4f5

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Communities (3)

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Causal emergence in biological systems
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Examines how macro-scale causal power exceeds micro-scale in living and learning systems.
Agential evolution & biological individuality
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Frames evolution as producing goal-directed, problem-solving agents across nested scales of individuality.
Substrate-independent associative learning in biological networks
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Learning and memory mechanisms (Pavlovian conditioning, pattern completion) emerge in gene regulatory and molecular networks through coarse-graining and causal emergence analysis.

Related by similarity (8)

cosine ≥ 0.65 · no typed edge

Entities in the same semantic neighborhood but without a typed relation to this one — candidates for new edges or unrecognized duplicates.

The genome does not merely specify chemical structures to be assembled but also specifies complex patterns of interaction between molecular structures required to produce controlled behaviours of the individual organism.claim0.810
An extension of the genetic code concept: it encodes developmental and behavioural control, not just static form.
Gene regulatory networks can evolve associative memory, storing and recalling multiple phenotypes from partial selective cues (Watson et al. 2010)finding0.801
Demonstrates information integration in evolutionary systems with system-level selection
The genome contains instead a program of instructions for making the organism — a generative program.quote0.785
Wolpert's core distinction, quoted by Alexander to support the generative approach to architecture.
If intercellular signalling (not genes) is the cognitive medium of a morphogenetic individual, it should be possible to exploit tools of neuroscience to read, interpret and re-write its information content for predictive control.claim0.781
Strong prediction from basal cognition framework; validated in planaria and other species through bioelectric manipulation.
Biology's robustness, open-endedness, evolvability, and unique complexity likely depend on the fact that evolution works with an agential material.claim0.780
Central claim linking life's properties to the inherent competencies of its material substrate.
The formation of centers is guided by generic patterns which play the role of genes.claim0.779
Analogy to biology, placing pattern languages as the genetic code for living built environments.
Physiological software dynamics, not genetic hardware, determine organism phenotype.claim0.778
Authors' central interpretive assertion: genome specifies cell-level components but outcome is product of dynamics not easily predicted from genetic sequence.
If intercellular signaling (not genes) is the cognitive medium of morphogenesis, then bioelectric signals can be read, interpreted, and rewritten to predictively control growth and form without genetic changes.hypothesis0.778
Predictive hypothesis validated in planarians and other species; enables therapeutic manipulation of morphogenetic targets.

Cross-corpus bridges (10)

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External markdown files that talk about the same concept as this entity.

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How do bioelectric patterns encode morphological information and control development independent of genetic sequence?questions/how-do-bioelectric-patterns-encode-morphological-information-and.md0.831
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How do biological systems encode anatomical information beyond DNA and gene expression?questions/how-do-biological-systems-encode-anatomical-information-beyond.md0.827
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How can bioelectric states encode and specify complex body plans independently of genetic information?questions/how-can-bioelectric-states-encode-and-specify-complex.md0.819
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What is the relationship between bioelectric patterns and gene expression in determining organismal form?questions/what-is-the-relationship-between-bioelectric-patterns-and.md0.818
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How do biological systems encode and recall anatomical target states independent of genetic specification?questions/how-do-biological-systems-encode-and-recall-anatomical.md0.818
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What is the relationship between genetic information and the emergent problem-solving behavior of living systems?questions/what-is-the-relationship-between-genetic-information-and.md0.814
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What is the relationship between genome and functional form in biological development?questions/what-is-the-relationship-between-genome-and-functional.md0.811
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What is the relationship between genetic specification, bioelectric patterning, and morphological form in development?questions/what-is-the-relationship-between-genetic-specification-bioelectric.md0.807
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What is the relationship between genome, software that produces bodies and behavior, and adaptive ends?questions/what-is-the-relationship-between-genome-software-that.md0.802
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To what extent does biological form derive from genetics versus from active interpretation of genetic resources?questions/to-what-extent-does-biological-form-derive-from.md0.790