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leiden_hybrid_concepts
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community:leiden_hybrid_concepts-run2-c143Planaria head/tail patterning stochasticity
Durant et al. 2017 documents fixed ~1:2 frequency of 1-head vs 2-head regeneration in cryptic fragments
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- Cryptic planaria exhibit stochastic but concordant head/tail decisionsBioelectrical disruption produces planaria forming 2-head or 1-head forms at ~70-30 ratio; randomization occurs at population level, but each worm makes unified decision across all tissues.
- Cryptic planaria fragments form 1-head and 2-head forms at a set frequency of ~1:2 (Durant et al. 2017)Shows stochastic anatomical outcome at the individual level while all cells in a fragment agree on one morphology.