Tononi & Cirelli (2006) — Sleep function and synaptic homeostasis

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• Synaptic Homeostasisconcept0.801
  Biological mechanism of sleep-dependent synapse elimination; analogous to Bayesian model reduction removing redundant parameters
• Homeostatic cycles as atoms of cybernetic systemsconcept0.740
• Homeostasis And Homeodynamicsconcept0.737
• Nocturnal sleep doubled the prevalence of insight-dependent performance improvements on a stimulus-response sequence task (Wagner et al., 2004).finding0.735
  Empirical support for sleep as facilitator of structure learning; consistent with BMR account
• Sleep implements Bayesian model reduction: non-REM sleep performs synaptic regression (complexity reduction) and REM sleep re-evaluates posteriors under the new reduced model.claim0.729
  Neurobiological interpretation linking sleep stages to distinct computational roles in model optimization
• Anatomical Homeostasisconcept0.722
  Ability of organisms to adjust anatomy despite injury or rearrangement; demonstrates collective problem-solving in morphospace.
• Anatomical homeostasis is a goal-seeking capacity of collective intelligence of cellular swarms; bioelectric networks controlled morphogenesis before controlling behavior.finding0.710
  Demonstrates that intelligence and goal-directedness operate in problem spaces beyond 3D behavioral space; supports basal cognition framework.
• All neuronal processing and action selection minimize variational free energy, unifying perception, action, and learning.claim0.710
  Fundamental assertion: single imperative (free energy minimization) explains diverse cognitive and neural phenomena.