artifact

active

artifact:evee

EVEE

Interpretable prediction tool for explaining genetic variant effects across the human genome.

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Papers (2)

paper

Explaining 4.2 million genetic variants with state-of-the-art, interpretable predictions
introduces
Covariance-based Sequence Pooling
associated_with

Frameworks (1)

framework

Evo-2
implements
Genomic foundation model used to predict and explain variant pathogenicity.

Artifacts (2)

artifact

Covariance-based Sequence Pooling (2026)
cites
Goodfire research post introducing covariance pooling as a replacement for mean pooling in genomic foundation models; shows +52.9% R² lift on genomic track prediction.
evee.goodfire.ai
implements
Web tool providing interactive access to EVEE predictions and disruption profiles.

Concepts (1)

concept

Variant pathogenicity prediction
about
Core task of predicting whether genetic variants cause disease, central to clinical genomics.